Protein Structure Prediction Services

At Biointelix, our Protein Structure Prediction Services empower researchers, biotech startups, and pharmaceutical companies to accelerate biomedical innovation. We provide advanced 3D modeling solutions that streamline drug discovery, vaccine development, and protein engineering, eliminating costly and time-consuming lab-based methods.

Example of Protein Structure Prediction Services

Structure Prediction of a Single-Chain Variable Fragment (scFv)

We generated this structural model from the amino acid sequence of an scFv using AlphaFold. Then, we refined and validated the model to ensure accuracy. Finally, we selected the highest-quality model based on structural integrity and confidence scores for downstream analysis.

Structure Prediction of a Single-Chain Variable Fragment against spike protein

In the 3D model:

The VH domain is shown in blue
The VL domain is shown in green
The linker region connecting them appears in yellow

For clarity, we color-coded the complementarity-determining regions (CDRs):

CDRs 1–3 of the VH domain are highlighted in red.
CDRs 1–3 of the VL domain are highlighted in orange.

This example demonstrates how Biointelix combines advanced AI-based modeling with expert refinement to deliver reliable structural insights for antibody fragments and other protein targets.

Why Protein Structure Prediction Matters

Understanding protein 3D structure is essential to interpret their function, interactions, and disease relevance. Since traditional methods like X-ray crystallography or cryo-electron microscopy can be costly, slow, or technically challenging, protein structure prediction offers a powerful computational alternative.

With Biointelix’s platform, you can:

Identify potential drug binding sites
Design or optimize therapeutic antibodies and enzymes
Explore molecular mechanisms behind disease
Support vaccine design with structural epitope mapping

How Our Protein Structure Prediction Works

We use state-of-the-art algorithms to predict a protein’s 3D conformation from its amino acid sequence. Our workflow combines several powerful methodologies:

Homology Modeling:

We align your target sequence with known templates to build reliable 3D models, modeling conserved and variable regions.

Ab Initio Folding Simulation:

When templates are unavailable, we simulate folding patterns to predict stable native structures.

Threading/Fold Recognition:

We scan your sequence against a fold library to find compatible frameworks, even with low sequence similarity.

Model Refinement and Validation:

We optimize side chains, refine geometry, and score models to ensure biological relevance. We validate all results with robust quality metrics.

What You Receive from Our Protein Structure Prediction Service

Choosing Biointelix means more than just obtaining a model. You receive:

High-resolution 3D protein models in PDB format
Confidence scores, domain annotations, and predicted functional sites
Interactive molecular visualization files
Optional add-ons: binding site prediction and ligand docking

Why Choose Biointelix for Protein Structure Prediction?

Deep Bioinformatics Expertise

Our specialists ensure every prediction is accurate, validated, and actionable.

Customized for Your Research

We tailor projects to your goals, whether drug screening, vaccine design, or exploring novel protein functions.

Fast and Reliable Turnaround

Most protein structure prediction reports are delivered within days, helping you move faster from idea to insight.

Confidential and Secure

We handle all your data with full confidentiality and encryption protocols.

Applications of Protein Structure Prediction Across Life Sciences

Our services enable many scientific advances, including:

Structure-based drug discovery
Therapeutic antibody and antigen design
Enzyme redesign for industrial use
Structural genomics and proteomics
Functional annotation of uncharacterized proteins

Get Started with Protein Structure Prediction Today

Unlock the power of accurate, computational protein structure prediction to advance your discovery pipeline. Whether you’re exploring a new therapeutic target or designing novel vaccines, Biointelix is your partner in structural insight.

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